📣 ADDS Atlanta 2026  |  February 23-25. Agenda is Now Available! Register Now!

THERAPEUTIC EXPERTISE

Solutions for Rheumatology and Immunology Research

Regulatory agencies have highlighted the need to assess physical function as key efficacy endpoints in clinical research involving rheumatic and immunological conditions. Wearable digital health technologies (DHTs) capture these real-world patient-centered outcomes continuously and remotely, increasing the probability of trial success and improving management of these conditions.

Schedule a Meeting Download the Guide

Opportunities with DHTs

  • Direct measures of real-world function
  • Demonstrate patient-centric benefits
  • Complement PRO-based evidence
  • Continuous, objective, low-burden data collection

Indications Where DHTs Have Been Included in Clinical Development

  • Rheumatoid Arthritis
  • Psoriatic Arthritis
  • Osteoarthritis
  • Ankylosing Spondylitis/Axial Spondylarthritis
  • Idiopathic Inflammatory Myopathy
  • Inclusion Body Myositis
  • Lupus
  • Sjörgen’s Syndrome
  • Palmoplantar Pustulosis
  • Myasthenia Gravis

Selected Digital Endpoints for Rheumatology and Immunology Research

Physical Activity

  • Moderate to Vigorous Physical Activity (MVPA)
  • Non-Sedentary Time
  • Step Count
  • 6 Minute Peak Activity

Gait & Mobility

  • Gait Speed / Cadence
  • Real-World 6-Minute Walk Distance
  • Distance
  • Morning Movement Pattern

Sleep

  • Wake After Sleep Onset (WASO)
  • Total Sleep Time
  • Sleep Efficiency
  • Sleep Onset Latency

Vital Signs

  • Heart Rate / Heart Rate Variability
  • Respiratory Rate
  • Oxygen Saturation
  • Blood Pressure
  • Skin Temperature
Physical Activity
  • Moderate to Vigorous Physical Activity (MVPA)
  • Non-Sedentary Time
  • Step Count
  • 6 Minute Peak Activity
Gait & Mobility
  • Gait Speed / Cadence
  • Real-World 6-Minute Walk Distance
  • Distance
  • Morning Movement Pattern
Sleep
  • Wake After Sleep Onset (WASO)
  • Total Sleep Time
  • Sleep Efficiency
  • Sleep Onset Latency
Vital Signs
  • Heart Rate / Heart Rate Variability
  • Respiratory Rate
  • Oxygen Saturation
  • Blood Pressure
  • Skin Temperature

Rheumatology and Immunology Digital Endpoint Guide

To learn more about opportunities with wearable digital health technologies in Rheumatology and Immunology clinical trials, download our full guide.

Download the Guide

Functional Assessments

People living with arthritis, myositis, and similar conditions are suffering from pain, weakness and stiffness on a daily basis that severely limit their physical functioning and mobility, and lead to poor sleep quality.

Wearable DHTs provide these patient-centered outcomes continuously and remotely, reducing the burden of trial participation, increasing the probability of trial success, and improving management of the conditions. Wearable data has shown that patients with arthritis not only move differently, but also that the movement patterns vary by time of day.

View Digital Outcomes and Biomarkers

Digital Health Monthly Webinar

Learn about AbbVie’s approach to addressing unmet needs in drug development in immunological diseases and how their team uses DHTs in clinical trials for better data collection, analysis, and integration into research trials.

Immunotherapy-Related
Adverse Events

Immunotherapies such as CAR-T cell therapy are promising advancements in the treatment of some immunological conditions such as Lupus and Rheumatoid Arthritis, but risk of serious adverse events such as cytokine release syndrome (CRS), neurotoxicity, and sepsis lead to prolonged hospital stays that can increase patient burden and trial costs.

Overcome these barriers with our remote patient monitoring platform and AI-powered risk monitoring. Continuous, remote monitoring of patient vital signs can reduce or eliminate prolonged hospitalization to reduce burden and cost while still prioritizing patient safety.

Download the Solution Sheet

Patient-Focused Digital Measures Reports

Access our Rheumatology and Immunology digital measure reports inspired by the FDA’s Patient-Focused Drug Development (PFDD) initiative, leveraging information from Voice of the Patient summaries to highlight how digital health technologies can help measure symptoms that are meaningful to patients.

Experience in Rheumatology and Immunology Trials

30
trials
1919
sites
44
countries
5043
participants